Original technology which has been passed clinical test(3rd phase)

      Why

Derived from PIG?

High Biocompatibility
Safety
- BSE FREE
- Qualified Original      Manufacturing Technique
Natural
B-TCP
​Propuct Description
Material
Type
Particle Size
Size
Porcine
Powder
Chip
0.2~1.0mm
1.0~2.0mm
0.15g / 0.36cc
0.25g / 0.6cc
0.5g / 1.2cc
1.0g / 2.4cc
0.25g / 0.9cc
0.5g / 1.8cc
1.0g / 3.6cc
2.0g / 7.2cc
Excellent Pore Structure
- Rough surface of microstructure makes osteoblast stick to the surface easily
- Reticular structure similar to cancellous bone secures sufficient space for     
  growing new bone
Easy Manipulation
- High wettability makes itself mix well with saline and blood
- Bone-XP is not easily scattered during the sinus lift procedure
High Wettability
- Stimulating new bone formation with great hydration with blood
- Osteoblast in blood helps the new bone formation
1. High Biocompatibility
100.00
​Classsification
Proximal = ~450
  Femur  = ~400
Bovine Bone
Human Bone
Porcine Bone
Young's module(MPa)
Ca/P ratio
B - TCP
Infection Risk
25.70
1.92
Absence
BSE
1.68 ~ 1.71
Exist
Cross Infection
346.33
83.15
1.66  ~  1.71
Controllable
N/A
Advanced biocompatible material
Similar!
2. Natural B - TCP
Hydroxtlapatite
CaO
B - TCP
a - TCP
98.5
1.21
0.25
0.04
100
1.0061
0.5909
1.7027
0.9975
0.0025
sum
Ca(atomic ratio)
P(atomic ratio)
Ca/P ratio
HA
B-TCP
Natural B-TCP yields
optimal Osteoconduction
and Osteoinduction
BSE Free!
 
Contrary to bovine bone, safe from BSE!
3. Clinical Case
Maxillary Sinus bone grafting & Buccal bone augmentation

Before the surgey     

      (Panorama)

Incision of gingiva

Sinus bone grafting with               Bone-XP

Implantation

Buccal bone augmentation

Applying collagen membrane Colla-D

Suture

After the surgery (Panorama)

Related Paper
​  Jung-Woog Shin et al..2004, In vitro studt of osteogenic differentitation of bone marrow stromal ceels on
  heat-treated porcine trabecular bone blocks, Biomaterials 25 (2004) 527-535
  Jung-Woog Shin et al..2009, Biocompatiblity Evaluation of Heat-treated Mineralized Porcine Cancellous
  Bone-Using anumal & Clinical Study ,J. of Korean Orthopaedic ResearchSociety Volume 12
  M.Figueiredo et al., 2010, Effect of the calcination temperature on the composition and microstructure of
  hydroxyapatite derived from human and animal bone, Ceramics international 36 (2010) 2383-2393
  Daniel N. Bracey et al., 2018, A Decellularized Porcine Xenograft-Derived Bone Scaffold for Clinical Use as a
  Bone Graft Substitute: A Critical evaluation of Precessing and Structure, J. Funct. Biomater.
  AI Pearce et al., 2007, Animal models for Implant biomaterial research in Bone : A review, European Cells and
  Materials Vol. 13. 2007
  

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